EVALUATION OF CALCIUM-SENSITIVE ADENYLYL CYCLASE AC1 AND AC8 MRNA EXPRESSION IN THE ANTERIOR CINGULATE CORTEX OF MICE WITH SPARED NERVE INJURY NEUROPATHY

The anterior cingulate cortex (ACC) is a critical region of the brain for the emotional and affective components of pain in rodents and humans.Hyperactivity in this region has been observed in neuropathic pain states in both patients and animal models and ablation of this region from cingulotomy, or inhibition with genetics or pharmacology can dimi

Benjamin J Thomas, Yoshihiro Yonekawa, Jeremy D Wolfe, Tarek S Hassan Department of Vitreoretinal Surgery, William Beaumont Hospital, Royal Oak, MI, USA Objective: To compare the effects of intravitreal ranibizumab (RZB) or dexamethasone (DEX) intravitreal implant in cases of recalcitrant diabetic macular edema (DME).Methods: Retrospective, interve

In this article, we will analyze how Minha Senhora de Mim (1971), by Maria Teresa Horta, confronted the dictatorship that was its zeitgeist, starting from the way she used canonical literature and literary traditional to challenge a Couple Enhancer specific status quo, bringing a new model of relationships between sexes to literature, contrasting w

The current focus in armor development is on the creation of lightweight, thin, and cost-effective solutions.This study explores innovative techniques by incorporating nanomaterials into composite plates, combined with fiber pre-stressing methods during the polymer matrix curing process.Woven Kevlar fibers experienced a pre-stress of 2 MPa in two d

Abstract Background Unexplained recurrent spontaneous abortion (URSA) is one of the most challenging conditions frustrates women of childbearing age profoundly.The gene expression patterns and biological characteristics of placental villus in patients with URSA remain largely unknown.The aim of our study was to identify potential lncRNAs as well as